VENTOLIN is a selective beta2 adrenoceptor agonist. At therapeutic doses it acts on the beta2 adrenoceptors of bronchial muscle, with little or no action on the heart.
Bronchodilators should not be the only or the main treatment in patients with severe or unstable asthma.
Severe asthma requires regular medical assessment as death may occur. Patients with severe asthma have constant symptoms and frequent exacerbations, with limited physical capacity, and Peak Expiratory Flow (PEF) values below 60% predicted at baseline with greater than 30% variability, usually not returning entirely to normal after a bronchodilator. These patients will require high dose inhaled (e.g >1 mg/day beclomethasone dipropionate) or oral corticosteroid therapy. Sudden worsening of symptoms may require increased corticosteroid dosage which should be administered under urgent medical supervision.