Vinblastine - intravenous

Patient Medicine Information
Why do I need this medicine?
Vinblastine is used on its own or together with other medicines to treat certain types of cancer of the lymph nodes, bone marrow, breast, kidney, testicles, or uterus (womb).

This medicine may be used to treat other conditions as decided by your doctor.
How do I use this medicine?
Vinblastine injection is to be given intravenously (into the vein). It is delivered directly into the bloodstream via the blood vessel.

Your doctor or nurse will administer the injection for you.

The dose of this medicine will be decided by your doctor. Your doctor will advise you on the course of treatment depending on the type and severity of your disease and your response to the medication.
What should I do if I have forgotten to use this medicine?
Ensure that you keep all appointments with your doctor so that you do not miss any doses. Your doctor also needs to regularly monitor your response to Vinblastine.

If you miss an appointment or miss an injection, alert your doctor or nurse. A replacement appointment or injection should be given as soon as possible.
When should I not use this medicine?
Alert your doctor if you have the following conditions:
  • untreated bacterial infection
  • low white blood cell count in the body
as Vinblastine may not be suitable for you.

Alert your doctor if you have been recently vaccinated. You must avoid any vaccinations without consulting with your doctor.
What should I take note of while using this medicine?
Inform your doctor if you have the following conditions:
  • heart disease
  • previous lung disease
  • liver disease
Let your doctor know if you are pregnant or breastfeeding.

It is important that you do not get pregnant while being treated with Vinblastine. You may wish to discuss birth control methods with your doctor or pharmacist.

This medicine can sometimes reduce fertility in men. Men who plan to have children should inform their doctor.

Vinblastine is not recommended to be administered in elderly people with poor health or skin sores.

For as long as you are being treated with this medicine, you may need to have regular blood tests (e.g. complete blood count, liver function tests, blood uric acid level) to check your body's response to the medicine. Your doctor will advise you about how often you need to have blood tests.
What side effects could I experience?
Vinblastine may cause any of the following side effects: headache, dizziness, nausea, vomiting, stomach pain, diarrhoea, constipation, mouth sores, loss of appetite, pain in the bones, muscles or jaw, pain in the area where the tumour is, hair loss, and blistering of the skin.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • pain or swelling at the injection site during or after the administration of this medicine
  • shortness of breath
  • chest pain, pressure, or tightness
  • pain, numbness, burning or tingling sensation in the hands or feet, weakness, fits or seizures
  • unusual bleeding or bruising
This medicine may cause the level of your white blood cells to drop.

White blood cells help your body to fight infections. A fall in the level of your white blood cells may put you at higher risk for infections, such as coughs, colds and flu, which may lead to more serious infections. Avoid crowded places and people who are sick. Inform your doctor if you have a fever, or a cough or flu that does not go away.

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I use this with other medicines?
Avoid vaccination with live vaccines during treatment with this medicine. Alert your doctor if you have been recently vaccinated or if you are planning to get vaccinated.

Inform your doctor and pharmacist if you are taking or using any of these medicines:
  • other medicines for cancer e.g. mitomycin, bleomycin, cisplatin
  • erythromycin (certain antibiotic)
  • phenytoin (medicine for fits or seizures)
This list does not include all medicines that may interact with Vinblastine.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in the refrigerator, between 2-8°C.

Do not freeze Vinblastine otherwise, it will no longer be effective and should not be used.

Protect from light.

Medicines must not be used past the expiry date.

As this is a cancer medicine, always return any unused or expired medicine to the clinic, hospital, or pharmacy for disposal.
This information is independently developed by MIMS based on vinblastine - intravenous and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2024 MIMS. All rights reserved. Powered by
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