Vomizole Tablet

Vomizole Tablet

pantoprazole

Manufacturer:

Dexa Medica
Concise Prescribing Info
Contents
Pantoprazole
Indications/Uses
Symptomatic GERD or nonerosive reflux disease (NERD). Long-term management of moderate & severe forms of reflux esophagitis.
Dosage/Direction for Use
GERD & NERD 20 mg daily for 2-4 wk. Reoccurring symptoms may be controlled w/ 20 mg once daily when required. Long-term management of moderate & severe form of reflux esophagitis Maintenance: 20 mg daily, increasing to 40 mg daily if relapse occurs. Reduce back to 20 mg after relapse is resolved. Patient w/ severe liver impairment Max: 20 mg once daily.
Administration
Should be taken on an empty stomach: Take 1 hr before meals. Swallow whole, do not chew/crush.
Contraindications
Hypersensitivity to pantoprazole or other substituted benzimidazole.
Special Precautions
Discontinue if liver enzymes rise. Monitor liver enzymes particularly in long-term use; Mg levels prior to treatment & periodically; prothrombin time/INR in patients concomitantly taking coumarin anticoagulants. Patients w/ reduced body stores or risk factors for reduced vit B12 absorption on long-term therapy; undergoing treatment >1 yr should be kept under regular surveillance; receiving multiple daily doses & on long-term therapy (≥1 yr). Exclude possibility of malignancy of gastric ulcer or esophagus prior to treatment. Hypomagnesemia. Increased risk of osteoporosis-related fractures of the hip, wrist or spine; Clostridium difficile-associated diarrhea especially in hospitalized patients. Severe liver impairment. Pregnancy & lactation. Childn.
Adverse Reactions
Leukopenia, thrombocytopenia; upper abdominal pain, diarrhea, constipation, flatulence, nausea/vomiting, dry mouth; peripheral edema; severe hepatocellular damage leading to jaundice w/ or w/o liver failure; anaphylactic reactions including anaphylactic shock; arthralgia, myalgia; headache, dizziness, disturbances in vision (eg, blurred vision); mental depression; interstitial nephritis; allergic reactions (eg, pruritus, skin rash), urticaria, angioedema, severe skin reactions eg, Stevens-Johnson syndrome, erythema multiforme, Lyell syndrome, photosensitivity.
Drug Interactions
May reduce absorption of drugs whose bioavailability is pH-dependent eg, ketoconazole. Changes in INR w/ phenprocoumon, coumarin anticoagulants & warfarin.
ATC Classification
A02BC02 - pantoprazole ; Belongs to the class of proton pump inhibitors. Used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD).
Presentation/Packing
Form
Vomizole Tablet EC tab 40 mg
Packing/Price
1 × 10's
Form
Vomizole Tablet EC tab 20 mg
Packing/Price
1 × 10's
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