Concise Prescribing Info
Vytorin 10/10 mg Ezetimibe 10 mg, simvastatin 10 mg. Vytorin 10/20 mg Ezetimibe 10 mg, simvastatin 20 mg
Adjunctive therapy to diet for the reduction of elevated total-C, LDL-C, Apo B, TG & non-HDL-C, & to increase HDL-C in primary (heterozygous familial & non-familial) hypercholesterolemia or mixed hyperlipidemia. Reduction of elevated total-C & LDL-C levels in homozygous familial hypercholesterolemia.
Dosage/Direction for Use
Dose range: 10/10-10/40 mg/day. Usual starting dose: 10/20 mg/day. Initiation of therapy w/ 10/10 mg/day may be considered for patients requiring less aggressive LDL-C reductions.
May be taken with or without food: Avoid excessive consumption (>1 L/day) of grapefruit juice.
Active liver disease or unexplained persistent elevations of serum transaminases. Pregnancy & lactation.
Special Precautions
Alcohol consumption &/or history of liver disease. Myopathy/rhabdomyolisis.
Adverse Reactions
Drug Interactions
Amiodarone or verapamil, diltiazem & potent CYP3A4 inhibitors.
ATC Classification
C10BA02 - simvastatin and ezetimibe ; Belongs to the class of HMG CoA reductase inhibitors in combination with other lipid modifying agents. Used in the treatment of hyperlipidemia.
Vytorin 10/10 mg tab
30's (Rp552,200/pak)
Vytorin 10/20 mg tab
30's (Rp552,200/pak)
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in