Individualised dosage. Bleeding & surgery: Minor
20-40 IU/dL every 12-24 hr for at least 1 day, depending on the severity of the hemorrhage. Moderate
30-60 IU/dL infusion every 12-24 hr for 3-4 days or until adequate wound healing. Tooth extraction
30-60 IU/dL single infusion + oral antifibrinolytic therapy w/in 1 hr. Major
60-100 IU/dL infusion every 8-24 hr until threat is resolved or until adequate wound healing in the case of surgery, followed by at least another 7 days therapy. Previously treated adult & adolescent Prophylaxis
30 ± 5 IU/kg given 3 times wkly.