The following convention has been used for the classification of adverse effects in terms of frequency: Very common ≥1/10, common ≥1/100 and <1/10, uncommon ≥1/1000 and <1/100, rare ≥1/10,000 and <1/1000, very rare <1/10,000.
Skin and Subcutaneous Tissue Disorders: Uncommon: Transient burning or stinging following application of Zovirax Cream, mild drying or flaking of the skin, itching. Rare: Erythema.
Contact dermatitis following application. Where sensitivity tests have been conducted, the reactive substances have most often been shown to be components of the cream rather than aciclovir.
Immune System Disorders: Very Rare: Immediate hypersensitivity reactions including angioedema.