Pheochromocytoma Disease Summary

Last updated: 10 October 2014

Overview

Pheochromocytoma is a rare adrenal gland catecholamine-secreting tumors arising from chromaffin cells that may precipitate life-threatening hypertension.
It can occur at any age but usually occurs during young to mid-adult life.
Majority of patients presents with ≥1 of the following hypertension resistant to standard antihypertensive treatment, hypertensive crisis with malignant hypertension, hypertensive encephalopathy, aortic dissection, or myocardial infarction and paroxysmal symptoms which suggest seizure disorder, anxiety attacks or hyperventilation.
Alpha-adrenergic blockade is the first-line therapy that is used to minimize complications prior to surgery.
Surgical intervention is the treatment of choice for most cases of pheochromocytoma.

For further information regarding the management of Pheochromocytoma, please refer to Disease Algorithm for the Treatment Guideline.