Actilyse

Actilyse Overdosage

alteplase

Manufacturer:

Boehringer Ingelheim

Distributor:

DKSH
Full Prescribing Info
Overdosage
Symptoms: If the maximum recommended dose is exceeded the risk of intracranial bleeding increases.
The relative fibrin specificity notwithstanding, a clinical significant reduction in fibrinogen and other blood coagulation components may occur after overdose.
Therapy: In most cases, it is sufficient to await the physiological regeneration of these factors after the ACTILYSE therapy has been terminated. If, however, severe bleeding results, the infusion of fresh frozen plasma or fresh blood is recommended and if necessary, synthetic antifibrinolytics may be administered.
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in