ADACEL is indicated for active booster immunization for the prevention of tetanus, diphtheria and pertussis (whooping cough) in persons 4 years of age and older.
Passive protection against pertussis in early infancy following maternal immunization during pregnancy (see Use in Pregnancy under PRECAUTIONS and DOSAGE & ADMINISTRATION).
ADACEL should be used in accordance with official recommendations.
In accordance with local recommendations, ADACEL may be considered as an alternative for the fifth dose of tetanus, diphtheria and acellular pertussis vaccine (DTaP) in children 4 through 6 years of age, concomitantly administered with Inactivated Poliomyelitis Vaccine (IPV) at separate sites to complete the vaccination series for this age, when indicated.
Persons who have had tetanus, diphtheria or pertussis should still be immunized since these clinical infections do not always confer immunity. Human Immunodeficiency Virus (HIV)-infected persons, both asymptomatic and symptomatic, should be immunized against tetanus, diphtheria and pertussis according to standard schedules.
ADACEL is not to be used for the treatment of disease caused by Bordetella pertussis, Corynebacterium diphtheriae or Clostridium tetani infections.
Pediatrics: ADACEL is not indicated for immunization of children below the age of 4 years.
Tetanus Prophylaxis in Wound Management: The need for active immunization with a tetanus toxoid-containing preparation such as Td Adsorbed vaccine or ADACEL, with or without passive immunization with Tetanus Immune Globulin, depends on both the condition of the wound and the patient's vaccination history. (See DOSAGE & ADMINISTRATION.)