Adult: 40 mg as a single dose every other wk. May increase to wkly dosing when used as monotherapy.
Ankylosing spondylitis, Psoriatic arthritis
Adult: 40 mg as a single dose every other wk.
Adult: Initially, 80 mg. Maintenance: 40 mg every other wk beginning 1 wk after 1st dose.
Juvenile idiopathic arthritis
Child: ≥4 yr 15 to <30 kg: 20 mg every other wk; ≥30 kg: 40 mg every other wk.
Crohn's disease, Ulcerative colitis
Adult: Moderate to severe active disease: Initially, 160 mg (given as four 40-mg inj in 1 day or as two 40-mg inj for 2 consecutive days), then 80 mg 2 wk after the initial dose (day 15). Maintenance: After 2 wk (day 29), 40 mg every other wk, may increase to 40 mg wkly if needed. Review treatment if no response w/in 8 (ulcerative colitis) or 12 (Crohn’s disease) wk of therapy.