Adipex Retard

Adipex Retard



Gerot Lannach


Concise Prescribing Info
Adjunctive therapy to diet in patients w/ obesity & BMI ≥30, who have not responded to an appropriate wt reducing regimen alone.
Dosage/Direction for Use
1 cap (15 mg) daily. In exceptional cases: Increase dose to 2 cap daily.
Should be taken with food: Take at breakfast. Avoid taking near bedtime. Swallow whole, do not chew/crush.
Hypersensitivity to other sympathomimetic amines. Pulmonary artery & severe arterial HTN. Current or past medical history of CV or cerebrovascular diseases & psychiatric disorders eg, anorexia nervosa & depression. Hyperthyroidism, pheochromocytoma, glaucoma, prostatic adenoma. Propensity towards drug abuse, known alcoholism. Combination w/ other centrally-acting anorectic agents due to increased risk of potentially fatal pulmonary artery HTN. Not to be used w/ MAOIs or w/in 2 wk after w/drawal of MAOIs. Renal insufficiency. 1st trimester of pregnancy. Lactation. Childn <12 yr. Elderly.
Special Precautions
Prolonged treatment may give rise to pharmacological tolerance & drug dependence & more rarely to severe psychotic disorders in predisposed patients. Ensure gradual & controlled wt loss in obese patients subject to risk of vascular disease. Epileptic patients. May affect ability to drive or operate machinery.
Adverse Reactions
Psychotic reactions or psychosis, depression, nervousness, agitation, sleep disorders, vertigo & convulsions; tachycardia, palpitations, HTN, precordial pain.
Drug Interactions
Reduced effect by phenothiazine & other psychotropic drugs eg, chlorpromazine, haloperidol & TCAs. Antagonized hypotensive effect of guanethidine & other antihypertensives. May cause hypertensive crisis w/ MAOIs. Potentiated effects by other CNS stimulants & caffeine. May lead to cardiac arrhythmias w/ inhalation anesth. Increased risk of potentially fatal pulmonary artery HTN w/ other centrally-acting anorectic agent.
MIMS Class
Anti-Obesity Agents
ATC Classification
A08AA01 - phentermine ; Belongs to the class of centrally acting antiobesity products. Used in the treatment of obesity.
Adipex Retard cap 15 mg
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