Spasmodic gastrointestinal complaints may occur very rarely. In these cases, a reduction of the dose is required. In the course of treatment, a harmless red colouring of the urine may appear.
After long-term use or higher doses (abuse), water and electrolyte balance disorders may occur. Incidents of diarrhoea may produce in particular potassium loss. Potassium loss can cause cardiac function disorders and myasthenia, in particular if cardiac glycosides, diuretics and cortisone and cortisone-like substances (adrenocortical steroids) are taken concurrently. In cases of chronic use, albumin or blood may be excreted in urine. Furthermore, staining of the intestinal mucosa (pseudomelanosis coli) may occur which, as a rule, is reversible after discontinuation of Agiolax. Very seldom hypersensitivity reactions to Plantago ovata may occur.