Agiolax

Agiolax

Manufacturer:

Mylan Healthcare

Distributor:

Antah Pharma
Full Prescribing Info
Contents
Psyllium, senna.
Description
Each 5 g of granules (equivalent to 1 teaspoonful or 1 sachet) contain Plantago ovata seeds 2.6 g, Plantago ovata husks 0.11 g, Cassia angustifolia pods 0.34-0.66 g equivalent to sennosides 15 mg.
It also contains the following inactive ingredients: Talc, acacia, iron oxides, paraffin, aromatics (eg, peppermint, sage and caraway oil) and sucrose.
Indications/Uses
Traditionally used for constipation.
Dosage/Direction for Use
Adults and Children >10 years: 1-2 tsp/sachets after the evening meal. The individually correct dose is the lowest dose required to achieve a soft-formed stool.
Do not take more than 2 tsp/sachets in a day.
Without medical advice, Agiolax should not be taken over a longer period. Please consult a healthcare practitioner for use beyond 7 days.
ADMINISTRATION: The granules should be swallowed whole with an abundant amount of liquid ie, ¼ L. When taking other medication, wait ½-1 hr before taking Agiolax.
Overdosage
In the event of inadvertent or deliberate overdose, painful intestinal spasms and severe diarrhoea with water and electrolyte losses as well as intense gastrointestinal complaints may occur.
Contraindications
Patients with abnormal stenoses in the gastrointestinal tract, ileus, diabetes mellitus that is difficult to control, acute inflammatory intestinal diseases eg, Crohn's disease, ulcerative colitis, appendicitis, abdominal pain of unknown cause, severe dehydration with water and electrolyte losses, children <10 years.
Special Precautions
Use for longer periods may worsen any existing bowel sluggishness. The preparation should be used only if constipation cannot be remedied by a change in diet or with the aid of bulking agents.
When Agiolax is taken by adult incontinent persons, prolonged contact of the skin with the faeces should be avoided by changing the sanitary towels.
Use In Pregnancy & Lactation
In the 1st trimester of pregnancy, Agiolax should be used only if constipation cannot be remedied by a change in diet or with the aid of bulking agents.
Degradation products of senna pods with a laxative action eg, rhein, pass in small amounts into the maternal milk. No laxative effect on breastfed babies was observed.
Side Effects
Spasmodic gastrointestinal complaints may occur very rarely. In these cases, a reduction of the dose is required. In the course of treatment, a harmless red colouring of the urine may appear.
After long-term use or higher doses (abuse), water and electrolyte balance disorders may occur. Incidents of diarrhoea may produce in particular potassium loss. Potassium loss can cause cardiac function disorders and myasthenia, in particular if cardiac glycosides, diuretics and cortisone and cortisone-like substances (adrenocortical steroids) are taken concurrently. In cases of chronic use, albumin or blood may be excreted in urine. Furthermore, staining of the intestinal mucosa (pseudomelanosis coli) may occur which, as a rule, is reversible after discontinuation of Agiolax. Very seldom hypersensitivity reactions to Plantago ovata may occur.
Drug Interactions
In cases of chronic use or abuse, the loss of potassium can potentiate the effect of cardiac glycosides and influence the action of antiarrhythmics. Loss of potassium can be enhanced in combination with certain diuretics, cortisone or cortisone-like substances (adrenocortical steroids) and liquorice roots.
The absorption of concurrently administered drugs from the gastrointestinal tract into the blood stream can be delayed. A reduction of the insulin dose can be required in insulin-dependent diabetics.
Storage
Store below 30°C.
Shelf-Life: 3 years.
ATC Classification
A06AB56 - senna glycosides, combinations ; Belongs to the class of contact laxatives.
Presentation/Packing
Granules (sachet) 5 g x 14's.
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