Heterozygous familial hypercholesterolaemia, Mixed dyslipidaemia, Nonfamilial hypercholesterolaemia
Adult: As monotherapy or adjunct to diet modification and statin therapy and other lipid-regulating agents: Initially, 75 mg once every 2 weeks, may increase to Max 150 mg once every 2 weeks. Alternatively, 300 mg once every 4 weeks. Patients requiring >60% LDL-C reduction or undergoing LDL apheresis: Initially, 150 mg once every 2 weeks. Dose is individualised according to response.