Taiwan Biotech


SS Health
Concise Prescribing Info
Short-term treatment of moderate or severe anxiety & anxiety associated w/ depression.
Dosage/Direction for Use
Anxiety 0.25 mg-0.5 mg tds, may be increased to 3 mg daily. Geriatric & debilitated patient 0.25 mg bd-tds. Duration: Not >8-12 wk.
May be taken with or without food: Side effects eg, sleepiness/drowsiness may be reduced if taken immediately after meals.
Hypersensitivity to benzodiazepines. Myasthenia gravis, severe resp & hepatic insufficiency, sleep apnoea syndrome. Lactation.
Special Precautions
Not to be used for short-term mild anxiety. Not recommended for the primary treatment of psychotic illness. Anaphylaxis & angioedema. History of alcohol or drug abuse. Rebound insomnia & anxiety. Amnesia, psychiatric & paradoxical reactions. Severely depressed or suicidal patients. Avoid abrupt discontinuation of treatment. May impair ability to drive & use machines. Renal or hepatic impairment. Avoid using in pregnancy, childn, elderly.
Adverse Reactions
Sedation/drowsiness, lightheadedness, numbed emotions, reduced alertness, confusion, fatigue, headache, dizziness, muscle weakness, ataxia, double or blurred vision, insomnia, nervousness/anxiety, tremor, change in wt, GI disturbances, changes in libido, skin reactions. Amnesia, depression, psychiatric & paradoxical reactions, dependence.
Drug Interactions
Enhanced sedative effect w/ alcohol. Enhanced central depressive effect w/ antipsychotics, hypnotics, anxiolytics/sedatives, antidepressants, narcotic analgesics, antiepileptics, anaesth & sedative antihistamines. Ketoconazole, itraconazole, azole-type antifungals, nefazodone, fluvoxamine, cimetidine, fluoxetine, propoxyphene, OC, sertraline, diltiazem, macrolides, ritonavir.
MIMS Class
ATC Classification
N05BA12 - alprazolam ; Belongs to the class of benzodiazepine derivatives anxiolytics. Used in the management of anxiety, agitation or tension.
Alpraline tab 0.5 mg
10 × 10's
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