Amdepin is indicated for the first-line treatment of hypertension and can be used as the sole agent to control blood pressure in a majority of patients. Patients not adequately controlled on a single anti-hypertensive agent may benefit from the addition of Amdepin, which has been used in combination with a thiazide diuretic, beta-adrenoceptor blocking agent, or an angiotensin converting enzyme inhibitor.
Amdepin is indicated for the first-line treatment of myocardial ischaemia,, whether due to fixed obstruction (stable angina) and/or vasospasm/vasoconstriction (Prinzmetal's or variant angina) of the coronary vasculature. Amdepin may also be used where the clinical presentation suggests a possible vasospastic/ vasoconstrictive component but where vasospasm/vasoconstriction has not been confirmed. Amlodipine may be used alone, as monotherapy, or in combination with other antianginal drugs in patients with angina that is refractory to nitrates and/or adequate doses of beta-blockers.