Concise Prescribing Info
Tramadol HCl
Moderate to severe acute & chronic pain & in painful diagnostic measure & surgery.
Dosage/Direction for Use
Cap Adult & adolescent >14 yr 50 mg, if pain relief is unsatisfactory take another 50 mg after 30-60 min. Max: Not to exceed 400 mg daily. Inj Adult & adolescent ≥12 yr 1-2 amp by IV inj/IV infusion/IM/SC. If pain relief is not obtained w/in 30-60 min, may give 2nd dose of 50 mg. Severe pain 2 amp as initial dose. Max: Not to exceed 400 mg daily.
May be taken with or without food.
Hypersensitivity. Resp depression, acute alcoholism, head injuries & increased intracranial pressure conditions. Not to be used in patients receiving MAOIs. Not to be used during pregnancy & lactation. Adolescents 12-18 yr who are obese & w/ obstructive sleep apnea or severe lung disease. Childn <18 yr after tonsils &/or adenoids removal.
Special Precautions
Resp depression; decreased resp reserves, hypoxia, hypercapnia; adrenal insufficiency; shock. Concomitant use w/ anesth, naloxone, benzodiazepines, serotonergic drugs, alcohol. Long-term use. May affect ability to drive & operate machines. Renal or hepatic impairment. Not recommended during pregnancy & lactation. Not recommended in childn <12 yr. Infants especially neonates. Cap: Not to be used for minor pain. Not to be given during bronchial asthma attack or in heart failure secondary to chronic lung disease, hypothyroidism, adrenocortical insufficiency, prostatic hypertrophy, inflammatory or obstructive bowel disorders, myasthenia gravis. Inj: Hypersensitivity to opiates. Not recommended as substitute in opioid dependence; reduced consciousness disorders of uncertain origin; increased intracranial pressure due to head injuries or brain diseases. Drug abuse or dependence.
Adverse Reactions
Allergic reactions & anaphylaxis; nausea, sweating, dry mouth, dizziness, lightheadedness, headache, motor weakness, change in appetite, blurred vision, micturition disorders, psychic effects, worsening asthma, epileptiform convulsion, increased intracranial pressure, bradycardia, dependence, increased liver enzymes, affect reaction; retching, vomiting, constipation, GI irritation, dermal reactions.
Drug Interactions
Not to be used w/ MAOIs. Enhanced depressant effects w/ CNS-depressant drugs eg, alcohol, anaesth, hypnotics & sedatives, TCAs, phenothizines. Precipitated w/drawal symptoms w/ buprenorphine, butorphanol, nalbuphine, pentazocine. Intensified sedative effects w/ tranquilizers. Increased risk of resp depression, profound sedation, coma & death w/ benzodiazepines. Serotonin syndrome w/ SSRIs, SNRIs, triptans, 5-HT3 receptor antagonists, mirtazapine, trazodone, tramadol, linezolid, IV methylene blue.
MIMS Class
ATC Classification
N02AX02 - tramadol ; Belongs to the class of other opioids. Used to relieve pain.
Analab inj 50 mg/mL
1 mL x 10 × 1's
Analab cap 50 mg
10 × 10's
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