Transfusion of D-positive blood components to rhesus-negative women of child-bearing potential
Adult: 125 units/ml of transferred cells.
Prevent formation of antibodies against fetal rhesus-positive RBCs in a rhesus-negative mother during childbirth, abortion or certain other sensitising events
Adult: 500 units as soon as possible after birth. An additional dose may be required depending on the amount of transplacental bleeding as assessed by the Kleihauer test; for bleeds >4 ml, an additional 125 units for each ml of RBCs will be required.
Routine antenatal prophylaxis
Adult: 2 doses of 500 units to be given at wk 28th and 34th of gestation.
Idiopathic thrombocytopenic purpura
Adult: Initially, 250 units/kg, may be given in 2 divided doses on separate days. Maintenance doses: 125-300 units/kg depending on the clinical response.