Anti-d immunoglobulin - intravenous

Patient Medicine Information
Why do I need this medicine?
Anti-D immunoglobulin is used to prevent formation of antibodies during pregnancy when a mother has Rh-negative blood and the baby is Rh-positive. It may also be given after a person with Rh-negative blood receives a transfusion with Rh-positive blood.

It is also used to treat immune thrombocytopenia (a blood disorder wherein there is very low platelet counts). Platelets help to clot blood.
How do I use this medicine?
Anti-D immunoglobulin injection is to be given intravenously into the vein. It is delivered directly into the bloodstream via the blood vessel.

Your doctor or nurse will administer the injection for you.
When should I not use this medicine?
Do not use Anti-D immunoglobulin if you ever had an allergic reaction (rashes, breathlessness, swollen eyes) to human immunoglobulin products.

Alert your doctor if you have the following conditions:
  • severe blood disorders
  • immunoglobulin A deficiency
  • Rh(D) positive (when used to prevent antibody formation)
  • Rh(D) negative previously sensitised to the Rh(D) antigen or have had your spleen removed (when used to treat ITP)
as Anti-D immunoglobulin may not be suitable for you.
What should I take note of while using this medicine?
Inform your doctor if you have bleeding disorders.

Let your doctor know if you are breastfeeding.

Inform your doctor if you have been recently vaccinated. Do not receive any vaccinations without first asking your doctor.

Your doctor may need to perform blood tests to check your response to this medicine.
What side effects could I experience?
Anti-D immunoglobulin may cause any of the following side effects: headache, dizziness, weakness, paleness, diarrhoea, nausea, vomiting, muscle or joint pain, rash, sweating and pain, redness, warmth and swelling at injection site.

If you develop rashes, breathlessness, swollen mouth or eyes, stop using Anti-D immunoglobulin and inform your doctor quickly. These could be signs of an allergic reaction.

When given for the treatment of idiopathic thrombocytopenic purpura, Anti-D immunoglobulin may cause some side effects that may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • back pain, chills, dark urine, shortness of breath or swelling of the hand or feet
  • unusual bleeding or bruising
  • unusual weakness or tiredness
  • unable to pass urine or decreased frequency of urination
  • troubled breathing
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I use this with other medicines?
Do not use Anti-D immunoglobulin with live attenuated vaccines (e.g. measles, mumps, rubella or varicella) during treatment and within 3 months after treatment with Anti-D immunoglobulin.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in the refrigerator, between 2-8 °C. Do not allow to freeze. If frozen, anti-D immunoglobulin will become ineffective and should not be used.

Protect from light.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on anti-d immunoglobulin - intravenous and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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