Enhanced blood glucose-lowering activity & increased susceptibility to hypoglycaemia by oral antidiabetics, ACE inhibitors, disopyramide, fibrates, fluoxetine, MAOIs, pentoxifylline, propoxyphene, salicylates, sulfonamide antibiotics. Reduced blood glucose-lowering activity by corticosteroids, danazol, diazoxide, diuretics, glucagon, INH, phenothiazine derivatives, somatropin, sympathomimetics, thyroid hormones, estrogens, progestins, PIs, atypical antipsychotics. Potentiated or weakened insulin effects by β-blockers, clonidine, lithium salts or alcohol. Hypoglycaemia followed by hyperglycaemia w/ pentamidine. Reduced or absent signs of adrenergic counterregulation w/ sympatholytics eg, β-blockers, clonidine, guanethidine, reserpine.