Discontinue use if myopathy is diagnosed & serious liver injury w/ clinical symptoms &/or hyperbilirubinemia or jaundice occurs. Recent stroke or transient ischemic attack. Substantial alcohol consumption &/or history of liver disease.
Co-administration w/ ketoconazole, spironolactone, cimetidine, gemfibrozil, fenofibrate & other fibrates, fusidic acid, warfarin, fluindione, cyclosporine, HIV & hepatitis C PI, erythromycin, clarithromycin, itraconazole, bocepravir, elbasvir, grazoprevir, niacin. May affect ability to drive & use machines. Not recommended in moderate to severe hepatic impairment. Not to be used during pregnancy & lactation.