Hypersensitivity. Monitor for clinical worsening, suicidal behaviour or thoughts & unusual changes in behaviour. Depressive patients w/ schizophrenic or schizoaffective psychoses, history of suicide-related events or suicidal ideation. Thyrotoxicosis, phaeochromocytoma. Avoid consumption of large amount of tyramine-rich food. Co-administration w/ multi-drug antidepressants, clomipramine. May affect ability to drive & use machines. Hepatic disease. Pregnancy & lactation. Childn & adolescent.