Axcel Cefuroxime Dosage & Drug Information

Concise Prescribing Info Local Product Insert

Concise Prescribing Info

Contents

Cefuroxime axetil

Indications/Uses

Upper & lower resp tract, GUT, skin & soft tissue infections, gonorrhoea, acute uncomplicated gonococcal urethritis & cervicitis. Oral susp Early lyme disease & subsequent prevention of late Lyme disease in adult & childn >12 yr.

Dosage/Direction for Use

Adult Most infections, mild to moderate lower resp tract infections eg, bronchitis, pyelonephritis 250 mg bd. More severe lower resp tract infections or suspected pneumonia 500 mg bd. UTI 125 mg bd. Pyelonephritis 250 mg bd. Uncomplicated gonorrhoea 1 g as single dose. Childn 125 mg bd. Max: 250 mg daily. Otitis media Childn >2 yr 250 mg bd or 15 mg/kg bd. Max: 500 mg daily, <2 yr 125 mg bd or 10 mg/kg bd. Max: 250 mg daily. Oral susp Lyme disease Adult & childn >12 yr 500 mg bd for 20 days.

Administration

Should be taken with food: Take immediately after meals.

Contraindications

Hypersensitivity to cephalosporins.

Special Precautions

Hypersensitivity to penicillins. Avoid prolonged use; patients concurrently treated w/ potent diuretics eg, frusemide. May cause pseudomembranous colitis. May affect ability to drive & use machines. Pregnancy & lactation.

Adverse Reactions

GI disturbances including diarrhoea, nausea & vomiting; pseudomembranous colitis; headache; eosinophilia, transient increases of hepatic enzymes.

View ADR Monitoring Form

Drug Interactions

Increased serum t_½ w/ probenecid. Lowered bioavailabity & tend to cancel effects of postprandial absorption w/ drugs reducing gastric acidity.

MIMS Class

Cephalosporins

ATC Classification

J01DC02 - cefuroxime ; Belongs to the class of second-generation cephalosporins. Used in the systemic treatment of infections.

Regulatory Classification

Presentation/Packing

Form

Axcel Cefuroxime cap 250 mg

Packing/Price

10's

Form

Axcel Cefuroxime oral susp 125 mg/5 mL

Packing/Price

50 mL x 1's

Axcel Cefuroxime

cefuroxime

Manufacturer:

Kotra Pharma

Distributor:

Kotra Pharma