Oral Azithro should be administered as a single daily dose.
Capsule should be taken at least 1 hour before or 2 hours after food.
The period of dosing with regard to infection is given as follows.
In Adults: For the treatment of sexually transmitted disease caused by Chlamydia trachomatis, Haemophilus ducreyi, or susceptible Neisseria gonorrhoeae: the dose is 1000 mg as single oral dose.
For prophylaxis against MAC infections: in patients with the human immunodeficiency virus (HIV), the dose is 1200 mg once per week.
For the treatment of DMAC infections: in patients with advanced HIV infection, the recommended dose is 600 mg once a day.
Azithro should be administered in combination with other antimycobacterial agents, such as ethambutol at the approved dose.
For all other indications in which the oral formulation is administered, the total dosage of 1500 mg should be given as 500 mg daily for 3 days.
In Children: Azithro capsules should only be administered to children weighing more than 45 kg the recommended dose as per adults.
In the Elderly: The same dosage as in adult patients is used in the elderly.
In Patients with Renal Impairment: No dose adjustment is necessary in patients with mild to moderate (GFR 10-80 ml/min) or severe (GFR <10 ml/min) renal impairment.
In Patients with Hepatic Impairment: The same dosage in patients with normal hepatic function may be used in patients with mild to moderate hepatic impairment.