Basalog One

Basalog One

insulin glargine

Manufacturer:

Biocon

Distributor:

Duopharma Marketing

Marketer:

Duopharma Marketing
Concise Prescribing Info
Contents
Insulin glargine (rDNA origin)
Indications/Uses
Adults, adolescents & childn ≥2 yr w/ DM where treatment w/ insulin is required.
Dosage/Direction for Use
10 IU once daily, subsequently adjusted to patient's needs. Total daily dose range: 2-100 IU. Type 1 diabetes ⅓ of total daily insulin requirements. Short-acting, pre-meal insulin should be used to satisfy the remainder of daily insulin requirements.
Special Precautions
Not to be given IV. Not for diabetic ketoacidosis. Allergic reactions. Hyper- & hypoglycaemia. Patients w/ significant stenoses of coronary arteries or risk of cardiac or cerebral hypoglycemic complications; proliferative retinopathy; in whom glycaemic control is markedly improved & hypoglycaemia develops gradually. Autonomic neuropathy, long history of diabetes, psychiatric illness; changed in inj area, improved insulin sensitivity, increased or prolonged physical activity, intercurrent illness, inadequate food intake, missed meals, alcohol consumption. Uncompensated endocrine disorders eg, hypothyroidism & anterior pituitary or adrenocortical insufficiency. Transferring from animal to human insulin. Combination w/ pioglitazone. May affect ability to drive & use machines. Renal & hepatic impairment. Pregnancy & lactation. Childn <2 yr. Elderly ≥65 yr.
Adverse Reactions
Hypoglycaemia, pyrexia. Lipohypertrophy; inj site reactions eg, redness, pain, itching, hives, swelling or inflammation.
Drug Interactions
Enhanced effect by oral antidiabetics, ACE inhibitors, disopyramide, fibrates, fluoxetine, MAOIs, pentoxifylline, propoxyphene, salicylates & sulphonamides. Reduced effect by corticosteroids, danazol, diazoxide, diuretics, glucagon, INH, oestrogens & progestogens, phenothiazine derivatives, somatropin; sympathomimetics eg, epinephrine, salbutamol, terbutaline; thyroid hormones, atypical antipsychotics eg, clozapine, olanzapine; PIs. Potentiated or weakened effect by β-blockers, clonidine, lithium salts or alcohol; pentamidine. Reduced or absent adrenergic counterregulation w/ β-blockers, clonidine, guanethidine & reserpine.
ATC Classification
A10AE04 - insulin glargine ; Belongs to the class of long-acting insulins and analogues for injection. Used in the treatment of diabetes.
Presentation/Packing
Form
Basalog One soln for inj 100 IU/mL
Packing/Price
3 mL x 1's;3 mL x 3 × 1's;3 mL x 5 × 1's
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