Not for protection against HIV infections & other STD. Increased risk of venous or arterial thromboembolic diseases; positive family history of venous or arterial thromboembolism, obesity, increasing age (>35 yr), smoking, cancer, SLE, haemolytic uraemic syndrome, Crohn's disease or ulcerative colitis, sickle cell disease; HTN, migraine, DM, hyperhomocysteinaemia, valvular heart disease, atrial fibrillation, dyslipoproteinaemia; benign or malignant liver tumours. History of herpes gestationis. Hypertriglyceridaemia, pancreatitis; chloasma. Epilepsy, multiple sclerosis, tetany, asthma, cardiac insufficiency, chorea minor, endometriosis, varicosis, phlebitis, blood coagulation disorders, mastopathy, uterine myoma, depression. Irregular vag bleeding. Prolonged immobilisation, major surgery or trauma, any leg or pelvis surgery. Perform medical exam including BP measurement, breast, abdomen, internal & external genital organs exam, cervical smear & appropriate laboratory tests prior to therapy. Concomitant use of St. John's wort, ombitasvir/paritaprevir/ritonavir & dasabuvir w/ or w/o ribavirin. Galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Acute or chronic hepatic function disturbances. Renal insufficiency. Not indicated during pregnancy. Not to be used during lactation.