Berberine


Concise Prescribing Info
Indications/Uses
Bacterial diarrhoea.
Dosage/Direction for Use
Adult : PO 1-2 tab bid.
Dosage Details
Oral
Bacterial diarrhoea
Adult: 1-2 tab bid.
Child: 5-15 years 1 tablet twice a day, 15 years Same as adult, or as directed by a physician.
Contraindications
Pregnancy, lactation. Infants & young children.
Adverse Reactions
High doses of berberine >500mg (corresponding to 8-100 g of dried goldenseal root) can cause stomach upset, nausea, vomiting, nervousness, depression, dyspnoea, bradycardia, cardiac damage, hypotension, seizures, paralysis, spasms & death.
Action
Description: Decreases anticoagulant effect of heparin in laboratory tests of heparinated animal & human blood. Act as cardiac stimulant in low doses, increases coronary perfusion & inhibits cardiac activity at high doses in animals. Antipyretic activity, anthelmintic, antihistaminic, antimicrobial, antimuscarinic, antitumorigenic & hypotensive effects have been documented in animals & laboratory models.
Duration: 8 hr.
Pharmacokinetics:
Absorption: Absorbs slowly orally. Peak plasma conc is achieved in 4 hr.
Excretion: Excretes in the urine.
Disclaimer: This information is independently developed by MIMS based on Berberine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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