Blopress

Blopress

candesartan

Manufacturer:

Takeda

Distributor:

DKSH
Concise Prescribing Info
Contents
Candesartan cilexetil
Dosage/Direction for Use
Initially 4 mg once daily, may be increased up to 16 mg once daily. Max duration: 4 wk. Elderly >75 yr, moderate to severe renal & mild to moderate hepatic impairment Initially 2 mg once daily.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Concomitant use w/ aliskerin-containing drugs in patients w/ diabetes or moderate to severe renal impairment (GFR <60 mL/min/1.73 m2). Pregnancy & lactation.
Special Precautions
Dual blockade of renin-angiotensin-aldosterone system. Bilateral renal artery stenosis or artery stenosis to solitary kidney; intravascular vol depletion; patients suffering from haemodynamically relevant aortic or mitral valve stenosis or obstructive hypertrophic cardiomyopathy. Periodic monitoring of serum K & creatinine levels. Not recommended in concomitant use w/ aliskiren-containing medicines. May affect ability to drive & use machines. Severe hepatic impairment. Not to be used during pregnancy. Lactation. Childn.
Adverse Reactions
Resp infection; dizziness/vertigo, headache.
Drug Interactions
Increased risk of hypotension, hyperkalemia & renal function changes w/ angiotensin-receptor blockers, ACE inhibitors or aliskerin. Reversible increased serum lithium conc & toxicity. Attenuated antihypertensive effect w/ NSAIDs ie, selective COX-2 inhibitors, acetylsalicylic acid, non-selective NSAIDs. Enhanced antihypertensive effects w/ other BP-lowering medicines. Increased serum K w/ K-sparing diuretics, K supplements or K-containing salt substitutes, heparin Na.
ATC Classification
C09CA06 - candesartan ; Belongs to the class of angiotensin II receptor blockers (ARBs). Used in the treatment of cardiovascular disease.
Presentation/Packing
Form
Blopress tab 16 mg
Packing/Price
14's
Form
Blopress tab 8 mg
Packing/Price
14's
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