Treatment of the following infections caused by susceptible strains: Respiratory tract infections caused by Mycoplasma pneumoniae; psittacosis due to Chlamydia psittaci; trachoma caused by Chlamydia trachomatis, although the infection is not always eliminated, as judged by the immunofluorescence; inclusion conjunctivitis caused by Chlamydia trachomatis; nongonococcal urethritis in adults caused by Ureaplasma urealyticum or Chlamydia trachomatis, chancroid due to Haemophilus ducreyi; cholera caused by Vibrio cholerae.
Treatment of infections caused by the following gram-negative microorganisms, when bacteriologic testing indicates appropriate susceptibility to the drug: Escherichia coli, Enterobacter aerogenes, Shigella and Acinetobacter spp; respiratory tract infections caused by Haemophilus influenzae; respiratory tract and urinary tract infections caused by Klebsiella sp.
Treatment of infections caused by the following gram-positive microorganisms, when bacteriologic testing indicates appropriate susceptibility to the drug: Upper respiratory tract infections caused by Streptococcus pneumoniae; skin and skin structure infections caused by minocycline-sensitive organisms; uncomplicated urethritis in men due to Neisseria gonorrhoeae, and for the treatment of other gonococcal infections when penicillin is contraindicated.
An alternative drug in the treatment of the following infections: Infections in women caused by Neisseria gonorrhoeae; syphilis caused by Treponema pallidum; listeriosis due to Listeria monocytogenes; anthrax caused by Bacillus anthracis; infections caused by Clostridium sp; in severe acne, minocycline may be used as an adjunct therapy.
Treatment of asymptomatic carriers of Neisseria meningitidis to eliminate meningococci from the nasopharynx. It is recommended that the prophylactic use of minocycline be reserved for situations in which the risk of meningococcal meningitis is high.
Also used in the treatment of infections caused by Mycobacterium marinum.