Brexin

Brexin

piroxicam beta-cyclodextrin

Manufacturer:

Chiesi

Distributor:

Germax
Concise Prescribing Info
Contents
Piroxicam-β-cyclodextrin (equiv to piroxicam 20 mg)
Indications/Uses
Symptomatic relief of OA, RA & ankylosing spondylitis eg, swelling, stiffness & joint pain.
Dosage/Direction for Use
Adult 20 mg as single daily dose. Elderly >70 yr Lower daily dose & reduce treatment duration.
Administration
Should be taken with food: Take immediately after meals.
Contraindications
Hypersensitivity to NSAIDs or aspirin. Stomach or intestinal ulcer, bleeding or perforation. History of GI disorders. HTN, blood alterations. Moderate or severe heart failure. Hemorrhagic diathesis. Patients taking anticoagulants. Severe hepatic & renal disease. Pregnancy & lactation. Childn <18 yr.
Special Precautions
Stomach pain & bleeding. Risk of heart attack or stroke. History of HTN &/or heart failure. Cardiocirculatory failure, poor renal perfusion, active or previous blood alterations. Concomitant use w/ diuretics. Asthmatic. Periodic ophth monitoring are advised during prolonged treatment. Perform frequent blood testing. Intolerance to some sugars. Avoid alcohol consumption. May affect ability to drive & use machines. Hepatic or renal impairment. Elderly >70 yr.
Adverse Reactions
Digestive tract ulcers & GI bleeding; nausea, vomiting, diarrhoea, flatulence, constipation, gastric acidity, abdominal pain, ulcerative stomatitis, colitis & Crohn's disease; ankles, legs & feet swelling; increased BP; heart failure.
Drug Interactions
Aspirin or other NSAIDs, corticosteroids, anticoagulants, SSRIs, diuretics, ACE inhibitors, angiotension II antagonists, lithium, quinolones, IUD.
MIMS Class
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
ATC Classification
M01AC01 - piroxicam ; Belongs to the class of non-steroidal antiinflammatory and antirheumatic products, oxicams.
Presentation/Packing
Form
Brexin tab 20 mg
Packing/Price
20's
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