Buprenorphine - transdermal

Patient Medicine Information
Why do I need this medicine?
Buprenorphine is used to treat severe chronic (long-term) pain.
How do I use this medicine?
Apply Buprenorphine patch on your skin exactly as directed by your doctor or according to the instructions on the label. Do not apply more or less than instructed by your doctor. Do not use it for a longer period of time than instructed by your doctor.

Instructions for application:
  1.  Remove the patch from the protective foil pouch and peel away half of the liner. Do not touch the sticky side with your fingers.
  2. Apply the patch to a clean, dry area. You can choose any area on your stomach, hip, thigh, shoulder, upper arm or flank (side of the body between the ribs and pelvis). Make sure that the area of skin is not oily, cut, blistered or irritated. The skin should be free of any powder, creams or lotions. If the area of skin is hairy, you should shave the area at least 3 days before you apply the patch. Do not put the patch near the waistline or where your belt or clothes may rub against it.
  3. Peel away the other half of the liner. Press firmly on the skin for 20-30 seconds to ensure that the patch stays on the skin.
  4. Replace the patch every 7 days. Do not apply the Buprenorphine patch to the same area of skin for at least the next 2 applications.
  5. Throw away the used patch by folding the sticky sides together and putting it in a rubbish bin. Do not throw it into the toilet bowl.
Avoid applying on skin that is red, inflammed, irritated or scarred.

If this patch falls off, apply a new patch to a new area of skin and change the patch at the usual time.

If the side of the patch lifts up, use a plaster or bandage to secure it to your skin.

Buprenorphine patch must be used regularly for it to be effective. Continue using Buprenorphine patch even when you feel better. Do not stop using it unless instructed otherwise, as stopping it suddenly could worsen your condition.
What should I do if I have forgotten to use this medicine?
Apply the missed dose as soon as you remember.

DO NOT double a dose under any circumstances.

If you often forget to apply your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you have:
  • lung disease (e.g. asthma)
  • a condition called “paralytic ileus” wherein the bowel does not work properly
  • myasthenia gravis (autoimmune disorder characterised by muscle weakness)
as Buprenorphine patch may not be suitable for you.

Do not use Buprenorphine patch together or within 2 weeks of taking a type of antidepressant known as MAO inhibitors, e.g. moclobemide, selegiline, phenelzine.
What should I take note of while using this medicine?
Inform your doctor if you have the following:
  • liver disease
  • kidney disease
  • head injury or brain disease
  • thyroid disease
  • prostate enlargement
  • mood disorders
  • excessive drinking or problems related to alcohol withdrawal
Let your doctor know if you are pregnant or breastfeeding.

Alert your doctor if you develop a fever while being treated with Buprenorphine patch. When you are feverish, more Buprenorphine than normal may be absorbed into your body and this may not be good for you. Avoid exposing the patch to heat such as heating pads, sauna, hot tubs and tanning lamps.
What side effects could I experience?
Buprenorphine patch may cause dizziness. If affected, do not drive or take part in any activity in which you need to be alert.

Other side effects include any of the following: headache, difficulty sleeping, anxiety or depression, nervousness, chills, nausea, loss of appetite, vomiting, stomach pain, constipation, dry mouth, sweating, back pain, itch or rashes at the site of application.

Notify your doctor immediately if you experience yellowing of the skin or eyes with abdominal pain or persistent tiredness, nausea or vomiting.

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I use this with other medicines?
Do not use Buprenorphine patch together or within 2 weeks of taking a type of antidepressant known as MAO inhibitors, e.g. moclobemide, selegiline, phenelzine.

Inform your doctor and pharmacist if you are taking any of these medicines:
  • medicines for fungal infections e.g. ketoconazole
  • medicines for epilepsy (fits or seizures) e.g. phenobarbital, carbamazepine
  • medicine for TB e.g. rifampicin
  • other painkillers such as morphine
  • medicine for sleep disorder e.g. diazepam, midazolam, alprazolam
  • cough medicine e.g. codeine, dextromethorphan
This list does not include all medicines that may interact with Buprenorphine.

Always notify your doctor and pharmacist if you are taking any other medicines including herbal tonics such as traditional Chinese medicine, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on buprenorphine - transdermal and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by MIMS.com
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