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Patients with severe liver impairment should be given a lower initial dose because they may have reduced clearance of Loratadine.
Use in Pregnancy and Lactation: The safe use of Loratadine during pregnancy has not been established. Therefore, Loratadine should only be given if the potential benefit justifies the potential risk to the fetus.
Use in Lactation: Loratadine is excreted in the breast milk, so nursing mothers are advised not to take the drug.
