Cefobid Caution For Usage







Full Prescribing Info
Caution For Usage
Special precautions for disposal and other handling: Intravenous Administration: Vials of cefoperazone sterile powder may be initially reconstituted with a minimum of 2.8 ml per gram of cefoperazone of any compatible reconstituting solution appropriate for intravenous administration listed below in Table 3. For ease of reconstitution the use of 5 ml of compatible solution per gram of cefoperazone is recommended. (See Table 3.)

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The entire quantity of the resulting solution should then be further diluted for administration using any of the following vehicles for intravenous infusion listed below in Table 4: (See Table 4.)

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Intramuscular Administration: Sterile Water for Injection or Bacteriostatic Water for Injection may be used to prepare cefoperazone for intramuscular injection. When concentrations of 250 mg/ml or more are to be administered, a lidocaine solution should be used. These solutions should be prepared using a combination of Sterile Water for Injection and 2% Lidocaine Hydrochloride Injection that approximates a 0.5% Lidocaine Hydrochloride Solution. A two-step dilution process as follows is recommended: First, add the required amount of Sterile Water for Injection and agitate until cefoperazone powder is completely dissolved. Second, add the required amount of 2% lidocaine and mix. (See Table 5.)

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