At therapeutic doses, Cetirizine does not potentiate the effect of alcohol (at a blood level of 0.8 g/l). Care should, however be taken. Activities requiring mental alertness: in clinical trials the occurrence of somnolence has been reported in some patients taking Cetirizine: due caution should therefore be exercised when driving a car or operating potentially dangerous machinery.
Effects on Ability to Drive and Use Machine: Studies in healthy volunteers on 20 or 25 mg/day have not revealed effects on alertness or reaction time. Patient should be advised, however to take care not to exceed the recommended dose.
Use in Children: The safety and effectiveness of Cetirizine in pediatric patients under the age of 2 years have not been established.