Cimetropium bromide


Concise Prescribing Info
Indications/Uses
GI tract spasm.
Dosage/Direction for Use
Adult : PO 50 mg 2-3 times/day.
Dosage Details
Oral
Gastrointestinal tract spasm
Adult: 50 mg bid-tid. May also be given via rectal suppository.
Contraindications
Prostatic enlargement, paralytic ileus or pyloric stenosis.
Special Precautions
Caution when used in patients with diarrhoea or fever. Thyrotoxicosis, heart failure and in cardiac surgery. Children, elderly. Not advisable for use in angle-closure glaucoma.
Adverse Reactions
Mouth dryness, reduced bronchial secretions, pupil dilatation with loss of accommodation and photophobia. Skin flushing and dryness, transient bradycardia followed by tachycardia, with palpitations and arrhythmias, and micturition difficulty, as well as reduction in tone and motility of the GI tract resulting in constipation.
Drug Interactions
Effects may be enhanced when used with drugs with antimuscarinic properties e.g. amantadine, some antihistamines, phenothiazines and TCAs. May antagonise the GI effects of cisapride, domperidone and metoclopramide.
Action
Description: Cimetropium bromide is a quaternary ammonium antimuscarinic. It has been used as an antispasmodic in the treatment of GI disorders
MIMS Class
Disclaimer: This information is independently developed by MIMS based on Cimetropium bromide from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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