Ciprox Special Precautions





Full Prescribing Info
Special Precautions
Ciprox should be used with caution in patients suffering from epilepsy and CNS disorders.
Crystalluria related to the use of ciprofloxacin has been reported.
Patients with a family history of or actual defects in glucose-6-phosphate dehydrogenase activity are prone to haemolytic reactions with quinolones. Older patients and those treated concurrently with corticosteroids might experience tendon inflammation and rupture. At the first sign of pain or inflammation, patients should discontinue ciprofloxacin and rest the affected limbs.
Patients should avoid prolonged exposure to strong sunlight or UV radiation during treatment. Ciprox could result in impairment of the patient's ability to drive or operate machinery, particularly in conjunction with alcohol.
Particular caution is advised in patients who need to concurrently take: antacids, any other preparations containing aluminium, calcium, magnesium or iron, anticoagulants (such as warfarin), medicines used to relieve pain and inflammation except aspirin, glibenclamide, probenecid or metoclopramide, cyclosporin, phenytoin.
Exacerbation of myasthenia gravis: Fluoroquinolones have neuromuscular blocking activity and may exacerbate muscle weakness in person with myasthenia gravis. Post marketing serious adverse events, including deaths and requirement for ventilator support have been associated with fluoroquinolones use in persons with myasthenia gravis. Avoid fluoroquinolones in patients with known history of myasthenia gravis.
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