Claritrox Tablet

Claritrox Tablet

clarithromycin

Manufacturer:

SM Pharmaceuticals

Distributor:

SM Pharmaceuticals
Concise Prescribing Info
Contents
Clarithromycin
Indications/Uses
Upper resp tract infections eg, strep pharyngitis/tonsillitis, acute maxillary sinusitis; lower resp tract infections eg, bronchitis, pneumonia; acute otitis media; skin & skin structure infections eg, impetigo, folliculitis, cellulites, abscesses.
Dosage/Direction for Use
Adult 250 mg every 12 hr for 7 days. Severe infections 500 mg every 12 hr for 14 days. Renal impairment ½ adult dose.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity to macrolide antibiotics. Co-administration w/ cisapride, pimozide, terfenadine, astemizole & ergot derivatives.
Special Precautions
Hypersensitivity to erythromycin & other macrolides. Pseudomembranous colitis; superinfection. Prolonged or repeated use. Hepatic & renal impairment. Not to be used during pregnancy & lactation.
Adverse Reactions
Diarrhoea, nausea, abnormal taste, dyspepsia, abdominal pain/discomfort, headache.
Drug Interactions
Increased plasma conc of carbamazepine, terfenadine, omeprazole. Increased serum conc of digoxin; cyclosporine, tacrolimus, hexobarbital, phenytoin, alfentanil, quinidine/disopyramide, lovastatin, bromocriptine, valproate, astemizole & other CYP450-metabolised drugs. Decreased serum conc by rifabutin or rifampin. Increased AUC of theophylline. Potentiated effects of warfarin. Acute ergot toxicity w/ ergotamine or dihydroergotamine. Severe adverse effects w/ non-sedative antihistamines, astemizole, terfenadine & cisapride. Lowered Cmax, AUC & tmax of zidovudine. Increased plasma conc by Maalox, ranitidine, omeprazole.
MIMS Class
ATC Classification
J01FA09 - clarithromycin ; Belongs to the class of macrolides. Used in the systemic treatment of infections.
Presentation/Packing
Form
Claritrox FC tab 500 mg
Packing/Price
10 × 10's
Form
Claritrox FC tab 250 mg
Packing/Price
3 × 10's
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