Comazole Dosage/Direction for Use

sulfamethoxazole + trimethoprim


SM Pharmaceuticals


SM Pharmaceuticals
Full Prescribing Info
Dosage/Direction for Use
(See Table 1.)
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Tablet: It may be preferable to take this tablet with some food or drink to avoid gastrointestinal disturbance.
Acute infection: Adults and children over 12 years old, standard dosage: 2 tablets every 12 hours.
Children 6 - 12 years, standard dosage: 1 tablet every 12 hours.
In acute infections, Comazole should be continued until the patient has been symptom free for 2 days, the majority will require treatment for at least 5 days. If clinical improvement is not evident after 7 days' therapy, the patient should be re-assessed.
For severe infections in all age groups, the dosage may be increased by 50%.
As an alternative to standard dosage for acute uncomplicated lower urinary tract infections, short term therapy of 1 - 3 days duration has been shown to be effective.
The treatment is about 10 - 14 days. An identical daily dosage is used for 5 days in the treatment of shigellosis. Patients with impaired renal function need a reduction of dosage. (See Table 2.)

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