Immediate hypersensitivity reactions. Discontinue if paradoxical bronchospasm occurs. Acute, rapidly worsening dyspnoea. Patients predisposed to glaucoma, insufficiently controlled DM, recent MI, severe organic heart or vascular disorders, underlying severe heart disease, hyperthyroidism, phaeochromocytoma, risk of narrow-angle glaucoma, prostatic hypertrophy or bladder-neck obstruction, hypoxia, cystic fibrosis. Hypokalaemia. May affect ability to drive & use machines. Hepatic or renal insufficiency. Pregnancy & lactation. Childn.