Individualize dosage, to be taken once daily in the morning. Dose may be adjusted in increments to max: 54 mg daily, at wkly interval. Patient new to methylphenidateAdult 18 or 36 mg once daily. Childn 18 mg once daily. Patient currently using methylphenidate 10-60 mg bd or tds.
Structural cardiac abnormalities. Onset or exacerbation of motor & verbal tics; growth suppression w/ long-term therapy; preexisting GI narrowing or w/ dysphagia; severe depression & fatigue; may exacerbate symptoms of behavior disturbance & thought disorder in psychotic patients; patients whose underlying conditions may be compromised by increases in BP or heart rate; history of drug dependence/alcoholism & seizures. Periodic hematologic monitoring during prolonged therapy. May impair ability to drive or operate machinery. Pregnancy & lactation.
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