Covinace

Covinace Adverse Reactions

perindopril

Manufacturer:

Pharmaniaga Manufacturing Berhad

Distributor:

Pharmaniaga Logistics
Full Prescribing Info
Adverse Reactions
Reported side effects are rare and benign. The most frequent complaints were often reported at the start of treatment, when blood pressure was poorly controlled: headaches, mood and/or sleep disturbances, asthenia.
Non-specific gastrointestinal disorders, such as taste disturbances, dizziness and cramps have been reported. Several localised skin rashes were also noted. A non-productive, irritating, dry cough were sometimes observed, though this caused little discomfort. Several other relatively non-specific side effects were often reported during multiple-agent therapy: sexual disorders, dryness of the mouth.
As far as the laboratory findings are concerned, a very slight reduction in haemoglobin was sometimes observed at the start of treatment. A slight increase in blood potassium levels, which returned to normal on combination with a hypokalemia diuretic, has been reported. Elevated blood urea and creatinine, reversible on interruption of treatment, was also observed.
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