Cozaar

Cozaar

losartan

Manufacturer:

Merck Sharp & Dohme

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Losartan K
Indications/Uses
HTN. Reduce risk of stroke in patients w/ HTN & left ventricular hypertrophy (LVH). Diabetic nephropathy w/ elevated serum creatinine & proteinuria in patients w/ type 2 diabetes & history of HTN.
Dosage/Direction for Use
HTN Usual starting & maintenance dose: 50 mg once daily for most patient. Max: Antihypertensive effect is attained 3-6 wk after initiation of therapy. Some patient may receive an additional benefit by increasing the dose to 100 mg once daily. HTN w/ LVH Usual starting dose: 50 mg once daily, may be increased to 100 mg once daily w/ low dose hydrochlorothiazide based on BP response. Renal protection in type 2 diabetic w/ proteinuria & HTN Usual starting dose: 50 mg once daily, may be increased to 100 mg once daily.
Administration
May be taken with or without food.
Contraindications
Special Precautions
Angioedema; intravascular vol depletion (eg, those treated w/ high-dose diuretics), electrolyte imbalance. Changes in renal function including renal failure may occur in susceptible individuals. Increased blood urea & serum creatinine in patients w/ bilateral renal artery stenosis or artery stenosis to solitary kidney. Hepatic impairment. Lactation. Childn.
Adverse Reactions
Abdominal pain, asthenia/fatigue, chest pain, edema/swelling; palpitation, tachycardia, hypotension; diarrhea, dyspepsia, nausea; back pain, muscle cramps; dizziness, headache, insomnia, vertigo; cough, nasal congestion, pharyngitis, sinus disorder, upper resp infection; hyperkalemia.
Drug Interactions
Rifampin & fluconazole. K-sparing diuretics, K supplements or K-containing salt substitutes, NSAIDs.
ATC Classification
C09CA01 - losartan ; Belongs to the class of angiotensin II receptor blockers (ARBs). Used in the treatment of cardiovascular disease.
Presentation/Packing
Form
Cozaar FC tab 100 mg
Packing/Price
30's
Form
Cozaar FC tab 50 mg
Packing/Price
30's
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