Breakthrough bleeding as in all cases of irregular vag bleeding, nonfunction causes should be considered. In cases of undiagnosed vag bleeding, adequate diagnostic measures should be taken. Discontinue treatment on missed abortion. Increased risk for thromboembolism. Avoid concurrent use w/ intravag prep. May cause local skin reaction or vag irritation due to sorbic acid. Severe hepatic insufficiency. May affect ability to drive & use machines. 2nd & 3rd trimesters of pregnancy. Not to be used during lactation.