Discontinue use if increased frequency or severity of migraine occurs. Not for protection against HIV infections & other STD. Increased risk of arterial & venous thrombotic & thromboembolic diseases; positive family history of venous or arterial thromboembolism, smoking, age, obesity, prolonged immobilization, major surgery or trauma, any leg surgery, dyslipoproteinemia, HTN, migraine, valvular heart disease, atrial fibrillation; DM, SLE, hemolytic uremic syndrome, Crohn’s disease or ulcerative colitis, sickle cell disease; benign or malignant liver tumors. Hypertriglyceridaemia, pancreatitis; hereditary angioedema exogenous estrogens; history of chloasma gravidum; GI disturbances. Irregular bleeding. Avoid sun or ultraviolet radiation exposure. Renal impairment. Not indicated during pregnancy & lactation. Not for pre-menarche & post-menopausal patients.