Discontinue in the event of missed miscarriage. Discontinue use if MI, cerebrovascular disorders, arterial or venous thromboembolism, thrombophlebitis or retinal thrombosis are suspected & symptoms of depression worsens. Epilepsy, migraine, asthma, cardiac dysfunction, diabetes; hormone-sensitive conditions. Use rectally if barrier methods of contraception are used or if patients suffer from vag infection (especially moniliasis) or recurrent cystitis or have recently given birth. Use vaginally if patients suffer from colitis or fecal incontinence. Hepatic & renal dysfunction. Not to be used during pregnancy & lactation.