Discontinue use if hypersensitivity reactions occur. Not to be inj intrathecally. History of allergy (eg, seafood allergy, hay fever, hives), sensitivity to contrast media, asthma. Increased risk for nephrogenic systemic fibrosis. Patients on β-blockers & w/ bronchial asthma; CV disease; low seizure threshold. Screen patients for renal dysfunction prior to initiation. May affect ability to drive & use machines. Peri-op liver transplant patients. Acute or chronic severe renal insufficiency. Not to be used during pregnancy. Lactation. Not recommended for angiography in childn <18 yr. Neonates <4 wk & infants up to 1 yr. Elderly ≥65 yr.