D-Cure Dosage/Direction for Use




Zuellig Pharma
Full Prescribing Info
Dosage/Direction for Use
Paediatrics: Prevention of deficiency 0-1 years 25000 IU (1 single-dose oral solution) every 8 weeks.
Prevention of deficiency 1-18 years 25000 IU (1 single-dose oral solution) every 6 weeks.
Treatment of deficiency 0-18 years 25000 IU (1 single-dose oral solution) once every 2 weeks for 6 weeks (followed by maintenance therapy of 400-1000 IU/day).
Administration to children: In children, D-Cure can be mixed with a small amount of children's foods, yogurt, milk, cheese or other dairy products. The parents should be warned not to mix D-Cure into a bottle of milk or container of soft foods in case the child does not consume the whole portion, and does not receive the full dose. The parents should ensure that their child takes the entire dose. For children who are not breast-fed, the prescribed dose should be administered with a meal.
Adults: Prevention of vitamin D deficiency 25000 IU/month (1 single-dose oral solution).
Treatment of vitamin D deficiency (<25 ng/ml) 50000 IU/week (2 single-dose oral solution) for 6-8 weeks, followed by maintenance therapy (1400-2000 IU/day may be required; follow-up 25(OH)D measurements should be made approximately three to four months after initiating maintenance therapy to confirm that the target level has been achieved).
As an adjunct to specific therapy for osteoporosis: 25000 IU/month (1 single-dose oral solution).
Administration to adults: D-Cure is an oral solution packaged in single-dose container. The content of the single-dose oral solution is to be emptied directly into the mouth and swallowed orally. To help the patient, the full content of the single-dose oral solution may be emptied onto a spoon and taken orally. D-Cure is only for oral use.
Certain populations are at high risk of vitamin D deficiency, and may require higher doses and monitoring of serum 25(OH)D: Institutionalised or hospitalised individuals;
Dark skinned individuals;
Individuals with limited effective sun exposure due to protective clothing or consistent use of sun screens;
Obese individuals;
Patients being evaluated for osteoporosis;
Use of certain concomitant medications (e.g., anticonvulsant medications, glucocorticoids);
Patients with malabsorption, including inflammatory bowel disease and coeliac disease;
Those recently treated for vitamin D deficiency, and requiring maintenance therapy.
Special populations: Renal impairment: D-Cure should not be used in combination with calcium in patients with severe renal impairment.
Hepatic impairment: No posology adjustment is required in patients with hepatic impairment.
Pregnancy and breastfeeding: The high strength formulation is not recommended.
Method of administration: Patients should be advised to take D-Cure preferably with meal (see Pharmacology: Pharmacokinetics: Absorption under Actions).
See Special Precautions for handling and disposal under Caution for Usage.
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