Dalacin C 150/Sterile Solution

Dalacin C 150/Sterile Solution

clindamycin

Manufacturer:

Pfizer

Distributor:

DKSH

Marketer:

DKSH
Concise Prescribing Info
Contents
Clindamycin HCl or phosphate
Indications/Uses
Upper & lower resp tract, skin & soft tissue, bone & joint, gynecological, intra-abdominal & dental infections; septicemia & endocarditis; toxoplasmic encephalitis & Pneumocystis jiroveci pneumonia in patients w/ AIDS.
Dosage/Direction for Use
Cap Adult 600-1,800 mg daily in 2, 3 or 4 equal doses. Childn >1 mth 8-25 mg/kg daily in 3 or 4 equal doses. β-hemolytic streptococcal infections Continue treatment for at least 10 days. Chlamydia trachomatis cervicitis 450 mg qds for 10-14 days. Toxoplasmic encephalitis in patient w/ AIDS 600-1,200 mg 6 hrly IV or PO for 2 wk followed by 300-600 mg PO 6 hrly. Duration: 8-10 wk. Pyrimethamine dose: 25-75 mg PO daily for 8-10 wk. Folinic acid dose: 10-20 mg daily. Pneumocystis jiroveci in patient w/ AIDS 600-900 mg 6 hrly or 900 mg 8 hrly IV or 300-450 mg PO 6 hrly for 21 days. Primaquine dose: 15-30 mg PO once daily for 21 days. Acute streptococcal tonsillitis/pharyngitis 300 mg bd for 10 days. IM/IV Adult Serious infection 2,400-2,700 mg daily in 2, 3 or 4 equal doses. Less complicated infections 1,200-1,800 mg daily in 3 or 4 equal doses. Max dose: 4,800 mg daily. Single IM doses of >600 mg are not recommended. Pelvic inflammatory disease 900 mg 8 hrly w/ gm -ve aerobic antibiotic, continue w/ 450-600 mg PO 6 hrly to complete 10-14 days of therapy. Childn >1 mth 20-40 mg/kg daily in 3 or 4 equal doses. Neonate <1 mth 15-20 mg/kg daily in 3 or 4 equal doses. Small premature infant Lower doses may be adequate.
Administration
May be taken with or without food: Swallow whole w/ a full glass of water & in an upright position.
Contraindications
Hypersensitivity to clindamycin or lincomycin.
Special Precautions
Not to be used in meningitis. Overgrowth of nonsusceptbile organisms. Pseudomembraneous colitis. Clostridium difficile-associated diarrhea. Perform hepatic & renal function test in prolonged therapy. Hepatic or renal impairment; diarrhea. Pregnancy & lactation. Newborn & infant.
Adverse Reactions
Pseudomembranous colitis; thrombophlebitis; diarrhea, abdominal pain; abnormal liver function test; maculopapular rash.
Drug Interactions
Antagonism w/ erythromycin. Enhanced neuromuscular blocking properties.
MIMS Class
ATC Classification
J01FF01 - clindamycin ; Belongs to the class of lincosamides. Used in the systemic treatment of infections.
Presentation/Packing
Form
Dalacin C 150 cap 150 mg
Packing/Price
100's
Form
Dalacin C Sterile Solution inj 300 mg/2 mL
Packing/Price
1's
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