Danazol - oral

Patient Medicine Information
Why do I need this medicine?
Danazol is used to treat endometriosis (growth of tissues outside the lining of the uterus).

This medicine may also be used to treat painful breasts lumps and an inherited form of angioedema (swelling of the face and throat).
How do I take this medicine?
Take Danazol exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Take this medicine consistently either always with or always without meals. Try to take it at the same time each day.

Danazol must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed by the doctor.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor or pharmacist know.
When should I not use this medicine?
Alert your doctor if you have the following conditions:

- liver disease
- kidney disease
- heart disease
- active or a history of blood clot disorder
- abnormal vaginal bleeding
- porphyria (an inherited disorder that may cause skin or nerve problems)
- tumour dependent on androgen (male sex hormone)
as Danazol may not be suitable for you.

Do not take Danazol if you are pregnant or planning to have a baby soon. If you become pregnant while being treated with this medicine, alert your doctor immediately. This medicine may cause harm to your unborn child. You must use proven birth control methods while taking Danazol.

Do not take this medicine if you are breastfeeding.
What should I take note of while using this medicine?
Inform your doctor if you have the following conditions:

- high blood pressure
- migraine
- epilepsy (fits or seizures)
- diabetes
- breast cancer
- polycythaemia (high red blood cell count)

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly. He may need to do routine liver and kidney function tests while you are being treated with Danazol. Monitoring of blood pressure, cholesterol and glucose level may also be needed. Your doctor will advise you about how often you need to have these tests.
What side effects could I experience?
Danazol may cause dizziness and problems with your eyesight. If affected, do not drive or take part in any activity in which you need to be alert or need to see clearly.

This medicine may cause any of the following side effects: headache, tiredness, nervousness, rashes, sleep disorders, acne, back pain, joint pain, nausea, vomiting, constipation, excessive sweating, deepening, hoarseness or instability of the voice, sore throat, weight gain, changes in appetite, hair loss, and swelling of the ankles, feet, or hand.

This medicine may also cause changes in menstrual cycle and breast size, vaginal dryness or irritation, and changes in sex drive. Discuss with your doctor if you are concerned about these side effects.

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:

- blood-thinning medicines e.g. warfarin
- medicines for diabetes e.g. tolbutamide
- cholesterol-lowering medicines e.g. simvastatin, atorvastatin, lovastatin
- medicines transplantedused in organ transplant or certain immune disorders e.g. tacrolimus, ciclosporin
- medicines for epilepsy (fits or seizures) e.g. carbamazepine
- alpha calcidol (type of Vitamin D)

This list does not include all medicines that may interact with Danazol.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on danazol - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2023 MIMS. All rights reserved. Powered by MIMS.com
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