Each vial contains bleomycin sulfate as a lyophilised powder which is equivalent to 15,000 IU bleomycin activity. Each vial contains 55-70% of bleomycin A2 and 25-32% of bleomycin B2.
Bleomycin sulfate is an antineoplastic antibiotic which is a purified mixture of glycopeptides produced by a fermentation process employing the actinomycetes Streptoverticillium species. The bleomycin mixture contains predominantly the A2 and B2 peptides.
Bleomycin sulfate is a white or yellowish white or cream coloured amorphous hygroscopic powder. It is very soluble in water, slightly soluble in dehydrated alcohol, and practically insoluble in acetone and ether.
DBL Bleomycin Sulfate for Injection is a white to cream coloured lyophilised powder or plug. When reconstituted in Water for Injection, the pH of the solution is approximately 5.